| Bone RA, Landrum JT, Dixon Z et al: Lutein and zeaxanthin in the eyes, serum and diet of human subjects. Exp Eye Res; 71(3):239-245. 2000
Bone RA, Landrum JT, Mayne ST et al: Macular pigment in donor eyes with and without AMD: a case-control study. Invest Ophthalmol Vis Sci; 42(l):235-240. 2001
Brown L, Rimm EB, Seddon JM et al: A prospective study of carotenoid intake and risk of cataract extraction in US men. Am J Clin Nutr; 70(4):517-524. 1999
Chew BP, Wong MW, Wong TS: Effects of lutein from marigold extract on immunity and growth of mammary tumors in mice. | Jonny Bowden, Ph.D., C.N.S. See book keywords and concepts | In addition to the high-quality protein, the lutein and zeaxanthin, the choline and phosphatidylcholine, eggs also contain trace amounts of more than fifteen vitamins and minerals; one jumbo egg contains 18 percent of the Daily Value for riboflavin (vitamin B2), 14 percent of the Daily Value for vitamin B12, and 29 percent of the Daily Value for the important cancer-fighting trace mineral selenium. Not only that, eggs make you look good! Their high sulfur content promotes healthy hair and nails. | Hyla Cass, M.D. See book keywords and concepts | Alpha-carotene, lutein, zeaxanthin, and lycopene are also carotenoids. Beta-carotene and alpha-carotene can be turned into vitamin A, which is important for the health of the eyes and the nervous system.
Antioxidants naturally complement one another, and taking one by itself in high doses can actually increase free-radical damage. Your best bet for restoring levels of carotenes is to boost your fruit and vegetable intake—which could help get rid of your gout, too! | Brigitte Mars, A.H.G. See book keywords and concepts | Constituents
Carotenoids (physalin, zeaxanthin, beta-carotene), vitamin C, vitamins Bj and B2, niacin, iron, selenium, zinc, linoleic acid, amino acids (tryptophan, arginine, leucine, isoleucine), polysaccharides, phenols, betaine, beta-sitosterol
Energetic Correspondences
• Flavor: sweet, slightly sour
• Temperature: neutral
• Moisture: moist
• Polarity: neutral (yin/yang)
• Planet: Mars/Venus
• Element: water
Contraindications
Avoid in cases of acute fever or dampness, such as diarrhea and bloating. Otherwise goji is considered very safe, even for daily consumption. | Jonny Bowden, Ph.D., C.N.S. See book keywords and concepts | They're a great source of lutein and zeaxanthin, two other carotenoids that, when working together, have shown enormous promise in protecting the eyes and helping to prevent macular degeneration and cataracts. Both alpha-carotene and beta-carotene convert in the body to vitamin A, which, in addition to being a great antioxidant and immune system stimulator, tur-bocharges the formation of a purple pigment in the eye called rhodopsin. | | It contains calcium, magnesium, potassium, vitamin C, vitamin K, beta-carotene, and even a little of the eye-healthy carotenoids, lutein and zeaxanthin. And let's not forget the fiber. One cup of the cooked stuff gives you almost 4 g of fiber (one cup raw gives you 2 g). All this in one of the lowest-calorie foods on the planet. worth knowing
Many members of the cabbage family contain goitrogens, naturally occurring substances that may interfere with the function of the thyroid gland. People with hypothyroidism would be wise to consume moderately. | Brigitte Mars, A.H.G. See book keywords and concepts | Constituents
Alginic acid, fucoidan, carrageenan, calcium, chromium, germanium, iodine, iron, phosphorous, potassium, bromine, magnesium, manganese, selenium, silica, zinc, mucopolysaccharides, mannitol, alginic acid, kainic acid, laminine, histamine, zeaxanthin, protein, beta-carotene, vitamins B2 and B12, vitamin C, vitamin D, vitamin E
Energetic Correspondences
• Flavor: salty
• Temperature: cool
• Moisture: moist
• Polarity: yin
• Planet: Venus/Neptune/Moon
• Element: water
Contraindications
Avoid bladder wrack in cases of hyperthyroidism or general weakness and coldness. | Jonny Bowden, Ph.D., C.N.S. See book keywords and concepts | It contains 72 mg of magnesium, 425 mg of potassium, a little bit of folate, the eye-friendly carotenoids lutein and zeaxanthin, and best of all, a really substantial 6V2 g of fiber per one medium artichoke (if you go for a large one, you get almost 9 g!). And that's all for a miserly 60 calories (okay, 76 if you're going for the big guy). A good nutritional deal no matter how you slice it. (Or, in the case of the artichoke, dig for it.)
Arugula
Arugula sure doesn't look like an aphrodisiac, but that's exactly what the ancient Egyptians and Romans considered it to be. | Tori Hudson, N.D. See book keywords and concepts | Carotenes include beta-carotene, alpha-carotene, cryproxanthin, gamma-carotene, zeaxanthin, lutein, and lycopene. Studies have shown that beta-carotene deficiency in the cervical cells plays an etiologic role in the development of cervical dysplasia.24 In addition, a significant decrease in plasma beta-carotene levels is found in women with either cervical dysplasia or cancer of the cervix.25
It has been suspected that carotenes like lycopene, found in tomatoes, are more responsible for an improvement in dysplasia than is beta-carotene or the other carotenes. | Marshall Editions See book keywords and concepts | It also helps prevent oxidative damage. zeaxanthin also prevents oxidative damage of the macula; take 3 mg with food. Taking 30 mg of zinc has been shown in some studies to be helpful for macular degeneration. Fish oils contain DHA, a substance concentrated in the retina of the eye, and the consumption of fish oils has been shown to reduce the risk of macular degeneration. Take a product that can give you 1,000 mg of DHA a day. Vitamin E complex acts as an antioxidant and has been shown to improve vision in people with age-related macular degeneration. Take 400 IU a day. | Steven G. Pratt, M.D. and Kathy Matthews See book keywords and concepts | My recommended goal is 12 milligrams of lutein daily, which provides a variable amount of zeaxanthin. Optimum amounts of zeaxanthin are not yet known.
Lutein All-Stars
1 cup cooked kale 23.7 mg.
1 cup cooked spinach 20.4 mg.
1 cup cooked collards 14.6 mg.
1 cup cooked turnip greens 12.1 mg.
1 cup raw spinach 3.7 mg.
1 cup cooked broccoli 2.4 mg.
Zeaxanthin All-Stars
1 large orange bell pepper 8 mg. 1 cup canned sweet yellow corn 0.9 mg.
1 raw Japanese persimmon 0.8 mg.
1 cup degermed cornmeal 0.7 mg. | Jonny Bowden, Ph.D., C.N.S. See book keywords and concepts | In 2001, the National Eye Institute conducted the Age-Related Eye Disease Study (AREDS), which involved more than 3,600
Natural Prescription for Preventing Macular Degeneration and Preserving Vision
Multivitamin: Containing at least 500 mg vitamin C, 400 IU vitamin E, and 15 mg beta-carotene
Zinc: 30-80 mg
Omega-3 fatty acids: 1,000 mg (1 g)
Lutein (and zeaxanthin): 10 mg for general prevention, 20-40 mg for someone who already has macular degeneration
Note: All dosages are daily dosages and in pill or capsule form unless otherwise noted. people. | | That diet effectively boosted the subjects' consumption of lutein about 400 percent and zeaxanthin about 300 percent. That same year it was found that the use of a lutein supplement can also increase the density of the protective macular pigment. You can, of course, get some lutein from foods such as spinach, kale, broccoli, and Brussels sprouts, though probably not enough to get the full therapeutic effect of supplements. | Hyla Cass See book keywords and concepts | Alpha-carotene, lutein, zeaxanthin, and lycopene are also carotenoids. Beta-carotene and alpha-carotene can be turned into vitamin A, which is important for the health of the eyes and the nervous system.
Antioxidants naturally complement one another, and taking one by itself in high doses can actually increase free-radical damage. Your best bet for restoring levels of carotenes is to boost your fruit and vegetable intake—which could help get rid of your gout, too! | Mary G. Enig See book keywords and concepts | Phytochemicals such as carotenoids, including a-carotene, (3-carotene, lutein, lycopene, and zeaxanthin, are important fat-soluble nutrients, which are vitamin-like plant substances. These phytonutrients are involved in numerous tissue functions playing major roles as antioxidants, and in the case of lutein and zeaxanthin, they are antioxidants that serve as light-absorbing pigments in the retina and are protective of the macula. Lutein and zeaxanthin are found in egg yolks. Tomatoes are a source of lycopene and zeaxanthin. | Ann M. Coulston and Carol J. Boushey See book keywords and concepts | Elevated retinal zeaxanthin and prevention of light-induced photoreceptor cell death in quail. Invest. Ophthal. Vis. Sci. 43,3538-3549.
151. Jahn, C, Wastemeyer, H, Brinkmann, C, Trautmann, S., Mayner, A., and Wolf, S. (2005). Macular pigment density in age-related maculopathy. Graefe's Archive for Clin. Exp. Ophthalmol. 243, 222-227.
152. Beatty, S., Murray, I. J., Henson, D. B., Carden, D., Koh, H, and Boulton, M. E. (2001). Macular pigment and risk for age-related macular degeneration in subjects from a Northern European population. Invest. Ophthalmol. Vis. Sci. 42, 439^146.
153. | | Supplementation with the carotenoids lutein or zeaxanthin improves human visual performance. Ophthalmic Physiol. Opt. 26, 362-371.
166. Bartlett, H. E., and Eperjesi, F. (2007). Effect of lutein and antioxidant dietary supplementation on contrast sensitivity in age-related macular disease: a randomized controlled trial. Eur. J. Clin. Nutr. 61, 1121-1127.
167. Coleman, H., and Chew, E. (2007). Nutritional supplementation in age-related macular degeneration. Curr. Opin. Ophthalmol. 18, 220-223.
168. Hammond, B. R. Jr., Johnson, E. J., Russell, R. M., et al. (1997). | Alan R. Gaby, M.D., Jonathan V. Wright, M.D., Forrest Batz, Pharm.D. Rick Chester, RPh., N.D., DipLAc. George Constantine, R.Ph., Ph.D. Linnea D. Thompson, Pharm.D., N.D. See book keywords and concepts | CHECKLIST FOR MACULAR
DEGENERATION
Nutritional
Rating
Supplements
Herbs p-
Lutein (page 548) and
Ginkgo biloba zeaxanthin
(page 681)
)
Multivitaminmultimineral (page t
559)
«
Zinc (page 614)
Uctrk
Beta-carotene
Bilberry (page 634) :
(page 469)
Carotenes (page 488)
(prevention) (lutein
[page 548], zeaxanthin, lycopene [page 548])
1
Selenium (page 584)
1
Vitamin C (page 604)
Vitamin E (page 609)
What are the symptoms of macular degeneration? | | Nutritional supplements that may be helpful Lutein (page 548) and zeaxanthin are antioxidants (page 467) in the carotenoid (page 488) family. These carotenoids, found in high concentrations in spinach, col-lard greens, and kale, have an affinity for the part of the retina where macular degeneration occurs. Once there, they protect the retina from damage caused by sunlight.10 Harvard researchers reported that people eating the most lutein and zeaxanthin—an average of 5.8 mg per day—had a 57% decreased risk of macular degeneration, compared with people eating the least. | Jonathan V. Wright, M.D. and Alan R. Gaby, M.D. See book keywords and concepts | A survey of 876 elderly individuals revealed that those whose intake of lutein plus zeaxanthin was high (top 20 percentile) were 56% less likely to have AMD, compared with those whose intake of these carotenoids was low (bottom 20 percentile).13 Lutein has been shown to accumulate in the macula, where it protects against the damaging effects of certain light wavelengths.14 The main dietary sources of lutein and zeaxanthin are dark green vegetables, particularly spinach and collard greens. | Russell L. Blaylock, M.D. See book keywords and concepts | All of the carotenoids, such as alpha and beta-carotene, lycopene, phytofluene, phytoene, canthoxanthin, lutein, and zeaxanthin, possess powerful antioxidant properties. Zinc, magnesium, and manganese can all neutralize free radicals. Zinc and manganese make up part of the antioxidant enzyme superoxide dismu-tase (SOD) which neutralizes the powerful superoxide free radical. The special fatty acid component called DHA, derived from omega-3-oils, has been shown to stimulate the production of SOD as well. | Neal D. Barnard and Bryanna Clark Grogan See book keywords and concepts | These are rich sources of certain antioxidants, called lutein8 and zeaxanthin, which protect the lens.9 Foods rich in vitamins C and E may help, too.10 You will find plenty of vitamin C in oranges, bell peppers, cantaloupe, strawberries, and kiwifruit. It also shows up in places you may not expect: cruciferous vegetables—broccoli, brussels sprouts, cauliflower, and kale—as well as tomatoes and sweet potatoes. Healthy sources of vitamin E include cooked spinach, soy milk, mangos, wheat germ, and, of course, most multivitamins. | Mike Adams See book keywords and concepts | Super zeaxanthin with Lutein (www.LEF.org)
Dry eyes
Dry eyes are uncomfortable but easy to treat. They're also usually nothing to worry about, unless of course they are a symptom of infection or a larger illness. Sometimes, dry eyes can be a symptom of the vascular disorder Raynaud's syndrome or an autoimmune disorder called Sjogren's syndrome. If you have symptoms such as pinkish-red eyes, vision changes, eye pain, and pus or discharge from your eyes in addition to eye dryness, then make an appointment with a naturopath immediately. | Jack Challem See book keywords and concepts | Supplemental lutein, some of which the body converts to zeaxanthin, increases the thickness of the macular pigment and can often improve visual acuity in people with macular degeneration and retinitis pigmentosa, an inherited eye disease.
How to Take Carotenoid Supplements
The best source of carotenoids is a diet rich in fruits and colorful, non-starchy vegetables. If you opt for supplements, it is important to obtain a combination of beta-carotene, lycopene, and lutein. Natural beta-carotene (from algae) is superior to the synthetic form. | James F. Balch, M.D. and Mark Stengler, N.D. See book keywords and concepts | Carotenoids (Carotenes)
Examples of carotenoids include beta carotene, alpha carotene, gamma carotene, beta zeacarotene, cryptoxanthin, lycopene, zeaxanthin, lutein, canthaxanthin, crocetin, cap-santhin).
Function: There are over 600 identified carotenoids. Approximately 50 act as precursors to vitamin A. Carotenoids are potent antioxidants, help with immune function, and are involved with the growth and the repair of tissues. | Earl Mindell See book keywords and concepts | Though surgery may slow its progress, there is no cure for macular degeneration, which is why prevention is so important.) zeaxanthin may also help protect against different forms of cancer by scavenging free radicals and decreasing the growth of tumor cells.
Food and Supplement Advice: zeaxanthin is found in substantial concentrations in watercress, Swiss chard, chicory leaves, beet greens, spinach, and okra. If your diet does not frequently include these greens, a good mixed carotenoid or antioxidant supplement with 30-130 mg. zeaxanthin taken daily with meals should be considered.
104. | Alan R. Gaby, M.D., Jonathan V. Wright, M.D., Forrest Batz, Pharm.D. Rick Chester, RPh., N.D., DipLAc. George Constantine, R.Ph., Ph.D. Linnea D. Thompson, Pharm.D., N.D. See book keywords and concepts | Protective effects of cruciferous vegetables were thought to be due to their high concentration of the carotenoids lutein (page 548) and zeaxanthin, as well as theit stimulatory effects on the breakdown of environmental carcinogens associated with prostate cancer.9
Meat and how it is cooked
Meat contains high amounts of arachidonic acid. Some by-products of arachidonic acid have promoted prostate cancer in animals. | Russell L. Blaylock, M.D. See book keywords and concepts | Most of us have heard of beta-carotene, but there are others such as alpha carotene, lutein, lycopene, canthoxanthin, zeaxanthin, and cryptoxanthin. Diets poor in fruit and vegetable intakes deprive us of these vital antioxidants.
In 1936, a Nobel Prize-winning biochemist by the name of Szent-Gyorgi isolated a factor from plants that had some rather unusual properties. He knew that seriously depriving an animal of ascorbic acid would engender bleeding gums and internal bleeding, and that the animal would finally die as a result of extreme sensitivity to stress—a condition we know as scurvy. | Steven G. Pratt, M.D. and Kathy Matthews See book keywords and concepts | We know for sure that as the lutein and zeaxanthin levels increase in the macula of the eye, there is a significant decrease in the amount of harmful light rays that reach the retinal cells that produce vision. There's seems to be little doubt that the lutein/zeaxanthin provide protection.
Most of us involved in AMD research feel that long before we can see clinical evidence of AMD, adverse events are occurring in the retina. Preliminary data from my studies of people at high risk for later development of AMD are highly supportive of this hypothesis. | Alan R. Gaby, M.D., Jonathan V. Wright, M.D., Forrest Batz, Pharm.D. Rick Chester, RPh., N.D., DipLAc. George Constantine, R.Ph., Ph.D. Linnea D. Thompson, Pharm.D., N.D. See book keywords and concepts | Other members of the antioxidant carotenoid family include cryptoxanthin, alpha-carotene, zeaxanthin, lutein (page 548), and lycopene (page 548). However, unlike beta-carotene, most of these nutrients are not converted to vitamin A in significant amounts.
Where is it found?
Dark green and orange-yellow vegetables are good sources of beta-carotene. It is also available in supplements. |
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